Are you ready to revolutionize our understanding of circular RNAs (circRNAs) and their role in heart disease? We’re seeking a highly motivated and talented computational biologist to join our team at the Jakobilab!
As a postdoctoral researcher in our lab, you’ll have the opportunity to contribute to the development of new features for circtools, our widely-used circRNA analysis software. You’ll work alongside world-class researchers and scientists who are passionate about advancing the field of circRNA research.
Our lab is committed to fostering a collaborative and inclusive research environment that values innovation, creativity, and teamwork. As a postdoctoral researcher in our lab, you’ll have access to cutting-edge resources, state-of-the-art facilities, and a supportive team of researchers who are dedicated to advancing the field of circRNA research.
If you’re ready to join our dynamic team, please submit your CV and a brief statement of research interests via our application portal. We look forward to hearing from you!
We are proud to release circtools 2.0 on GitHub and the accompanying paper on bioRxiv in collaboration with the Dieterich Lab.
Circtools 2.0 features 4 completely new modules for computational circular RNA research:
Tobias was invited to present at the reImagine Health Symposium on Artificial Intelligence in Medical Practice and Research at The University of Arizona, College of Medicine Phoenix. Fantastic conference with great speakers, highlighting the importance as well as pitfalls of the use of AI in medical practise and research.
The new bioinformatics course (CTS 505, see teaching) serves as an introductory exploration into the fundamental principles, algorithms, and practical application of bioinformatics in hypothesis-driven research spanning basic and translational domains. The curriculum encompasses key protein and nucleotide alignment algorithms like BLAST and Smith-Waterman, essential public databases, RNA biology, and various approaches for DNA and RNA sequencing.
A new, large-scale circRNA detection benchmarking studies has just been published in Nature Methods, including our circtools circRNA detection suite. The study is the largest to date including 16 circRNA detection tools. The paper is a very good read for everyone interested in optimizing circRNA detection accuracy and efficacy.
Vivien Kmietczyk from the lab of Mirko Völkers in Heidelberg, Germany just published her newest paper, “Ythdf2 regulates cardiac remodeling through its mRNA target transcripts” in the Journal of Molecular and Cellular Cardiology! Congratulations! In the study we found that m6A the reader protein Ythdf2 controls cardiac function and identified a novel mechanism how reader proteins control gene expression and cardiac function.